CALL FOR PAPERS Integrative and Translational Physiology: Inflammation and Immunity in Organ System Physiology Impairment of heme biosynthesis induces short circadian period in body temperature rhythms in mice
نویسندگان
چکیده
Reiko Iwadate, Yoko Satoh, Yukino Watanabe, Hiroshi Kawai, Naomi Kudo, Yoichi Kawashima, Tadahiko Mashino, and Atsushi Mitsumoto Department of Pharmaceutical Sciences, Faculty of Pharmacy, Keio University, Minato-ku, Tokyo, Japan; Faculty of Pharmaceutical Sciences, Josai International University, Togane, Chiba, Japan; and Faculty of Pharmaceutical Sciences, Josai University, Sakado, Saitama, Japan
منابع مشابه
Impairment of heme biosynthesis induces short circadian period in body temperature rhythms in mice.
It has been demonstrated that the function of mammalian clock gene transcripts is controlled by the binding of heme in vitro. To examine the effects of heme on biological rhythms in vivo, we measured locomotor activity (LA) and core body temperature (T(b)) in a mouse model of porphyria with impaired heme biosynthesis by feeding mice a griseofulvin (GF)-containing diet. Mice fed with a 2.0% GF-c...
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